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Candida-associated denture stomatitis in type 2 diabetes mellitus
Barbara Dorocka-Bobkowska1, Dorota Zozulinska-Ziolkiewicz, Bogna Wierusz-Wysocka
1Department of Prosthetic Dentistry, Poznan University of Medical Sciences, Bukowska 70, Poznan, Poland. b.dorocka@gmail.com
Diabetes Research and Clinical Practice
|July 20, 2010
Summary
Candida-associated denture stomatitis (DS) is more common in type 2 diabetes (T2DM) patients, especially with poor glycemic control. Burning mouth sensation and dry oral mucosa were frequent complaints, linked to extensive inflammation.
Area of Science:
- Oral Medicine
- Diabetology
- Mycology
Background:
- Type 2 diabetes (T2DM) is a systemic condition affecting oral health.
- Denture stomatitis (DS) is a common oral condition in denture wearers, often associated with Candida species.
- Glycemic control significantly impacts the severity and presentation of oral conditions in diabetic patients.
Purpose of the Study:
- To characterize the clinical presentation of Candida-associated denture stomatitis (DS) in individuals with type 2 diabetes (T2DM).
- To investigate the relationship between DS types, oral symptoms, and associated oral conditions.
- To assess the correlation between these oral findings and glycemic control, measured by HbA1c.
Main Methods:
- A cross-sectional study involving 110 edentulous patients with T2DM and 50 control subjects.
- Data collection included demographic information, oral examinations, and questionnaires.
- Glycemic control was assessed using glycated hemoglobin (HbA1c) levels.
Main Results:
- Type II DS was significantly more prevalent in T2DM patients (57.3%) compared to controls (30%).
- Oral complaints, including burning sensation (BS) and dryness of the oral mucosa (DOM), were more frequent in diabetic individuals.
- Higher HbA1c levels correlated with more extensive DS inflammation and increased oral complaints.
Conclusions:
- The diffuse type of denture stomatitis is associated with T2DM.
- Burning mouth sensation and dry oral mucosa are common oral complaints in diabetic patients with DS.
- Inadequate glycemic control in T2DM patients with Candida-associated DS is linked to a higher incidence of extensive inflammation and oral complications.
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