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Updated: Mar 10, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Home dampness and molds as determinants of allergic rhinitis in childhood: a 6-year, population-based cohort study
Jouni J K Jaakkola1, Bing-Fang Hwang, Maritta S Jaakkola
1Jaakkola, Institute of Health Sciences, Aapistie 1, P.O. Box 5000, 90014 Oulu, Finland. jouni.jaakkola@oulu.fi
Insights
Exposure to dampness and mold in homes significantly increases the risk of children developing allergic rhinitis. This population-based study highlights indoor environmental factors as key determinants of this common childhood allergy.
Area of Science:
- Environmental Health
- Pediatric Allergy
- Epidemiology
Background:
- Indoor dampness and mold exposure are potential risk factors for respiratory conditions.
- Allergic rhinitis is a prevalent condition in childhood with significant health implications.
- Understanding environmental triggers is crucial for preventing childhood allergies.
Purpose of the Study:
- To investigate the association between indoor dampness and mold exposure and the incidence of allergic rhinitis in children.
- To identify specific indicators of dampness and mold that contribute to allergic rhinitis development.
- To strengthen the evidence base for the role of indoor environmental quality in childhood allergic diseases.
Main Methods:
- A 6-year, population-based prospective cohort study involving 1,863 children (aged 1-7 years).
- Parent-administered questionnaires assessed exposure to water damage, moisture, visible mold, and mold odor.
- Logistic regression analysis adjusted for potential confounding factors to determine the risk of allergic rhinitis.
Main Results:
- Any indicator of mold or dampness exposure was associated with an increased risk of allergic rhinitis.
- Adjusted odds ratios for mold/dampness exposure were 1.55 at baseline, 1.62 at follow-up, and 1.96 for both.
- Water damage and surface moisture were consistently identified as significant determinants of allergic rhinitis.
Conclusions:
- Indoor dampness and mold problems are significant independent determinants of allergic rhinitis in children.
- The findings provide strong evidence linking specific indoor environmental exposures to the onset of allergic rhinitis.
- This study underscores the importance of addressing indoor dampness to prevent childhood allergic rhinitis.
Abstract:
The authors assessed the relation between exposure to dampness and molds in dwellings and the development of allergic rhinitis in childhood in a 6-year, population-based prospective cohort study of 1,863 children aged 1-7 years at baseline in 1991 (follow-up rate, 77%) from Espoo, Finland. The studied exposures were history of water damage, presence of moisture and visible mold, and perceived mold odor in the home, based on parent-administered questionnaire. A total of 246 (13.2%) children developed physician-diagnosed allergic rhinitis during the study period, resulting in an incidence rate of 440 cases per 10,000 person-years (95% confidence interval (CI): 387, 499). In logistic regression adjusting for confounding, any mold or dampness exposure indicator at baseline (adjusted odds ratio = 1.55, 95% CI: 1.10, 2.18), at follow-up (adjusted odds ratio = 1.62, 95% CI: 1.21, 2.18), or both (adjusted odds ratio = 1.96, 95% CI: 1.29, 2.98) was an important independent determinant of the risk of allergic rhinitis. Of the individual indicators, water damage and moisture on the surfaces were consistent determinants of allergic rhinitis. The results of this cohort study, which assessed exposure before the onset of allergic rhinitis, strengthen considerably the evidence of the role of indoor dampness problems as determinants of allergic rhinitis in children.
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