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Functional analysis of the SRV-1 RNA frameshifting pseudoknot

René C L Olsthoorn1, Richard Reumerman, Cornelis W Hilbers

  • 1Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands. olsthoor@chem.leidenuniv.nl

Nucleic Acids Research
|July 20, 2010
PubMed
Summary

Simian retrovirus type-1 (SRV-1) uses a triple helix in its RNA pseudoknot to control protein expression. This structure is crucial for programmed ribosomal frameshifting, essential for viral replication.

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