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Related Concept Videos

Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cancer-Critical Genes I: Proto-oncogenes01:33

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancers Originate from Somatic Mutations in a Single Cell02:21

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Cancer Survival Analysis01:21

Cancer Survival Analysis

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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Cancer genetics.

S Goff1, C Jacobs, L Robinson

  • 1St Joseph's Hospice, London, UK. sheila.goff@btinternet.com

European Journal of Cancer Care
|July 21, 2010
PubMed
Summary
This summary is machine-generated.

This module explains how cancer genetics advances affect patient care, especially for those with a family history of cancer. Understanding genetic impacts improves personalized cancer management.

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Area of Science:

  • Oncology
  • Medical Genetics

Background:

  • Advances in cancer genetics are rapidly evolving.
  • Understanding these developments is crucial for clinical practice.

Purpose of the Study:

  • To educate health professionals on the impact of cancer genetics.
  • To highlight implications for patient care, particularly for individuals with a cancer family history.

Main Methods:

  • This module utilizes a review of current literature and clinical guidelines.
  • It synthesizes information on genetic testing, hereditary cancer syndromes, and risk assessment.

Main Results:

  • Health professionals will gain knowledge of genetic predispositions to cancer.
  • The module clarifies how genetic information influences diagnosis, treatment, and surveillance strategies.
  • It emphasizes the importance of genetic counseling for affected families.

Conclusions:

  • Integrating cancer genetics knowledge enhances patient care and outcomes.
  • Health professionals are better equipped to manage patients with hereditary cancer risk.
  • This educational module supports evidence-based practice in oncology.