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Postoperative urinary stone analysis-influence of the hydrogel retrieval method on stone analysis
C Jacobs1, F I Winterhagen2, M Ritter3
1Urinary Stone Analysis Center, Urologie Bonn-Rhein-Sieg, Bonn, Germany.
World Journal of Urology
|August 1, 2025
Summary
Properly washing hydrogel after urinary stone treatment ensures accurate analysis. Unwashed hydrogel interferes with infrared spectroscopy, but recommended washing preserves stone composition results.
Area of Science:
- Urology
- Biomaterials
- Analytical Chemistry
Background:
- Accurate urinary stone analysis is vital for tailoring metaphylaxis in recurrent urolithiasis.
- Hydrogel (mediNik®, Farco) was developed to enhance stone-free rates post-treatment.
- Investigating the impact of hydrogel on stone analysis is crucial for clinical application.
Purpose of the Study:
- To determine if hydrogel use affects urinary stone analysis.
- To assess the influence of different washing protocols on hydrogel-treated stone samples.
Main Methods:
- A randomized prospective blinded study involving 78 urinary stone analyses.
- Samples were analyzed before and after hydrogel treatment using Fourier transform infrared spectroscopy (ATR technique).
- Three washing groups were compared: manufacturer's instructions, EDTA only, and no washing.
Main Results:
- Stone analysis remained consistent in 100% of cases when hydrogel was washed per manufacturer's instructions or with EDTA.
- No stone composition could be determined in the unwashed group due to interference from additional bands.
- The hydrogel itself did not alter stone composition when properly removed.
Conclusions:
- Postoperative urinary stone analysis using IR spectroscopy is not compromised by hydrogel when washed as recommended.
- Standard hydrogel removal protocols ensure 100% accurate stone analysis, comparable to samples without hydrogel.
- This validates the use of hydrogel in urolithiasis management without compromising diagnostic accuracy.
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