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Updated: Jun 10, 2026

Experimental Approach to Examine Leptin Signaling in the Carotid Bodies and its Effects on Control of Breathing
Published on: October 25, 2019
Circulating leptin levels in elderly subjects with and without cerebrovasular disease
Anila Jalil1, Shahila Amir, Rehan Majeed
1Department of Biochemistry, Ziauddin University, Karachi. aneelajaleel@hotmail.com
Abstract:
Serum concentrations of leptin was investigated in 40 patients with ischemic stroke, in context of the size of the lesion and also in 40 non-diseased controls, matched according to age, gender and waist hip ratio. Serum leptin concentrations were determined in ng/ml with ELISA and computer tomography (CT) scan was performed in patients to estimate lesion size in cms. Serum leptin concentrations were found to be significantly higher (p < 0.001) in stroke patients (51.61+1.39), compared with controls (37.76+1.207). Moreover, positive correlation (r=0.93) existed between serum leptin level and infarction size in patients with stroke.
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