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Multiple Sclerosis l: Introduction01:19

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Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
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A home-based walking program using rhythmic auditory stimulation improves gait performance in patients with multiple

Dwyer Conklyn1, Darlene Stough, Eric Novak

  • 1The Music Settlement, Cleveland, OH, USA.

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|July 21, 2010
PubMed
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Rhythmic auditory stimulation (RAS) improved multiple sclerosis (MS) patients' gait parameters, including speed and cadence. This home-based intervention shows promise for enhancing walking ability in MS patients.

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Home-Based Monitor for Gait and Activity Analysis
07:24

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Published on: August 8, 2019

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Biomedical Engineering

Background:

  • Gait dysfunction is a significant challenge for multiple sclerosis (MS) patients, with limited successful interventions.
  • Rhythmic auditory stimulation (RAS) has shown efficacy in improving gait in other neurological conditions.

Purpose of the Study:

  • To evaluate the impact of RAS on quantitative gait parameters in ambulatory individuals with MS.
  • To assess the feasibility and safety of home-based RAS for MS patients.

Main Methods:

  • A randomized controlled trial involving 10 MS patients with gait disturbance.
  • Participants received 2 weeks of RAS (20 minutes daily) using MP3 players with music tempo adjusted to their cadence, followed by 2 weeks of cross-over.
  • Quantitative gait analysis was performed using the GAITRite system.

Main Results:

  • Significant reduction in double-support time was observed.
  • Trends towards improvement in walking speed and other gait parameters were noted.
  • Pooled analysis revealed significant improvements in cadence, stride length, step length, velocity, and normalized velocity after one week.

Conclusions:

  • Home-based RAS is feasible and safe for MS patients with gait impairment.
  • RAS demonstrates potential benefits for improving quantitative gait parameters in MS.