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Related Concept Videos

Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

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Related Experiment Video

Updated: Jun 10, 2026

Training Laboratory Rabbits to Refine Routine Husbandry Procedures
05:21

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Published on: February 16, 2024

Guidelines for reporting experiments involving animals: the ARRIVE guidelines.

J C McGrath, G B Drummond, E M McLachlan

    British Journal of Pharmacology
    |July 24, 2010
    PubMed
    Summary
    This summary is machine-generated.

    The British Journal of Pharmacology now requires adherence to the ARRIVE guidelines for reporting animal research. These guidelines enhance the transparency and reproducibility of in vivo experiments in pharmacology.

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    Area of Science:

    • Pharmacology
    • Translational Medicine
    • Animal Research Ethics

    Background:

    • Introduction of the ARRIVE (Animals in Research: Reporting In Vivo Experiments) guidelines for standardized reporting of animal studies.
    • Joint publication of ARRIVE guidelines across multiple journals to promote consistent research standards.
    • Editorial highlights the significance of these guidelines for the scientific community.

    Discussion:

    • Specific considerations for applying ARRIVE guidelines within the field of pharmacology.
    • Reiteration of the British Journal of Pharmacology's (BJP) existing author guidelines for animal experiments.
    • Emphasis on the journal's commitment to ongoing discourse regarding animal research reporting.

    Key Insights:

    • Enhanced transparency and reproducibility in in vivo research through standardized reporting.
    • Improved quality of scientific publications involving animal models.
    • Facilitation of critical appraisal and replication of research findings.

    Outlook:

    • Encouraging feedback from the scientific community on the ARRIVE guidelines via the British Pharmacological Society website.
    • Promoting wider adoption and implementation of the ARRIVE guidelines in pharmacological research.
    • Fostering a culture of responsible and ethical conduct in animal experimentation.