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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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Related Experiment Video

Updated: Jun 10, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

Published on: May 31, 2024

Pyodermatitis-pyostomatitis vegetans after subtotal colectomy for ulcerative colitis.

Asuka Kitayama¹, Noriyuki Misago, Takeshi Okawa

¹Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan. asuka-k@kanazawa-med.ac.jp

The Journal of Dermatology

|July 24, 2010

Summary

This case report details pyodermatitis-pyostomatitis vegetans in a patient with ulcerative colitis. Mucocutaneous lesions correlated with rectal inflammation relapse post-colectomy.

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Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Area of Science:

Gastroenterology
Dermatology
Immunology

Background:

Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
Subtotal colectomy is a surgical option for severe UC.
Mucocutaneous manifestations can occur in inflammatory conditions.

Observation:

A 51-year-old woman with a history of UC and subtotal colectomy presented with facial, scalp, gingival, and anal lesions.
Histopathology suggested pemphigus vegetans, but immunofluorescence and serological tests were negative.
Colonoscopy revealed a relapse of UC in the remaining rectal mucosa.

Findings:

A diagnosis of pyodermatitis-pyostomatitis vegetans was established.
This represents the first reported case of these lesions coinciding with UC relapse post-colectomy.
A strong correlation was observed between bowel inflammation activity and mucocutaneous lesion severity.

Implications:

Highlights a rare association between ulcerative colitis relapse and pyodermatitis-pyostomatitis vegetans.
Suggests a potential link between gut inflammation and specific mucocutaneous conditions.
Emphasizes the importance of considering gastrointestinal status in diagnosing unusual skin and mucosal lesions.