Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Saccades simulated with rhesus monkey innervation data.

J D Enderle1, E J Engelken, J Nelson

  • 1Department of Electrical & Electronics Engineering, North Dakota State University, Fargo 58105.

Biomedical Sciences Instrumentation
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced glycation alters expression of the 67kDa laminin receptor in retinal microvascular endothelial cells.

Life sciences·2001
Same author

A model of the internal control system within the superior colliculus.

Biomedical sciences instrumentation·2001
Same author

Improving design project experiences through improved assessment practices.

Biomedical sciences instrumentation·2001
Same author

Multi-position eye movement detection system.

Biomedical sciences instrumentation·2001
Same author

Novel keratin 17 mutations in pachyonychia congenita type 2.

The Journal of investigative dermatology·2001
Same author

Electron self-exchange kinetics in two average-valence dicopper cryptates.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry·2001
Same journal

EFFECT OF FILTERING KINEMATICS ON FINITE ELEMENT SIMULATIONS OF HEAD IMPACTS IN HIGH SCHOOL FEMALE LACROSSE.

Biomedical sciences instrumentation·2026
Same journal

INHIBITING THE INHIBITOR: WOULD TARGETING PAI-1 RESULT IN A LOW-DOSE, WELL-TOLERATED TREATMENT OF EMPYEMA?

Biomedical sciences instrumentation·2026
Same journal

QUANTIFYING HEAD IMPACT EXPOSURE, MECHANISMS AND KINEMATICS USING INSTRUMENTED MOUTHGUARDS IN MALE HIGH SCHOOL LACROSSE.

Biomedical sciences instrumentation·2026
Same journal

UTILITY OF CHEST ULTRASONOGRAPHY IN QUANTIFYING CLOT AND PLEURAL EFFUSION VOLUME IN PRECLINICAL MODELS OF PLEURAL DISEASE.

Biomedical sciences instrumentation·2026
Same journal

THE ROLE OF PERIPHERAL VISION IN ENHANCING BALANCE AND POSTURAL STABILITY: INSIGHTS FROM CENTRAL VISION OBSTRUCTION.

Biomedical sciences instrumentation·2025
Same journal

IMPACT OF NON-SKID SOCKS AND ANTERIOR WEIGHT ON POSTURAL RESPONSE AND STABILITY DURING PERTURBATION.

Biomedical sciences instrumentation·2025
See all related articles

This study simulates saccades using rhesus monkey neural data and an updated oculomotor plant model. The model accurately reproduces eye movement data, validating its robustness for studying neural control of gaze.

Area of Science:

  • Neuroscience
  • Oculomotor Systems
  • Computational Biology

Background:

  • Understanding the neural control of eye movements is crucial for diagnosing and treating visual disorders.
  • Previous models of the oculomotor plant have limitations in accurately simulating saccadic eye movements.

Purpose of the Study:

  • To develop and validate a robust computational model of the oculomotor plant for simulating saccades.
  • To test the model's ability to reproduce physiological eye movement data using neural input from rhesus monkeys.

Main Methods:

  • Extracellular single-unit recordings from abducens nucleus neurons (Long Lead Burst, Medium Lead Burst, Burst Tonic) in rhesus monkeys during horizontal saccades.
  • Utilized magnetic coil technique for eye position data collection.
  • Developed a linear, viscoelastic model of the oculomotor plant, including lateral and medial rectus muscles and the eyeball, driven by filtered motoneural signals.

Related Experiment Videos

Main Results:

  • Simulated saccades using the updated oculomotor plant model showed good agreement with experimental eye position data.
  • Higher derivatives of eye position, crucial for saccade dynamics, were also accurately reproduced by the model.
  • The model demonstrated robustness in simulating saccadic eye movements based on physiological neural input.

Conclusions:

  • The updated oculomotor plant model, driven by physiological neural data, provides a robust platform for simulating saccadic eye movements.
  • This validated model can be used to further investigate the neural mechanisms underlying gaze control.
  • The findings contribute to a better understanding of the relationship between neural activity and eye movement generation.