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Comparative effectiveness research: evaluating pharmacist interventions and strategies to improve medication
Barry L Carter1, J W Foppe van Mil
1Department of Pharmacy Practice and Science, College of Pharmacy, Iowa City, Iowa, USA. barry-carter@uiowa.edu
Physician and pharmacist collaboration effectively controls blood pressure (BP). Pharmacy interventions improve medication adherence and intensify treatments, but study designs and suboptimal regimens need improvement for better BP management.
Area of Science:
- Health Services Research
- Cardiovascular Medicine
- Pharmacy Practice
Background:
- Achieving optimal blood pressure (BP) control is a significant challenge in primary care.
- Physician/pharmacist collaborative management is an effective strategy for BP control.
- Pharmacy interventions can improve medication adherence and treatment intensification.
Purpose of the Study:
- To evaluate the strengths and weaknesses of research study designs assessing pharmacy interventions for BP control.
- To assess strategies for measuring medication adherence in research and clinical practice.
- To propose improvements for interventions and study designs in team-based care for BP control.
Main Methods:
- Review of health services' research study designs.
- Evaluation of medication adherence measurement strategies.
- Analysis of pharmacy interventions in primary care settings.
Main Results:
- Pharmacy interventions significantly reduce BP through improved adherence and medication intensification.
- Suboptimal medication regimens are a common cause of inadequate BP control.
- Existing research designs have limitations in assessing the full impact of pharmacy interventions.
Conclusions:
- Collaborative physician/pharmacist management is key to effective BP control.
- Enhanced study designs and interventions are needed to address suboptimal regimens.
- Future research should focus on robust comparative effectiveness trials for team-based BP management.
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