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Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Metabolic States of the Body: Fasting and Starvation01:24

Metabolic States of the Body: Fasting and Starvation

During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
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Related Experiment Video

Updated: Jun 10, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Migraine exacerbation during Ramadan fasting.

Ibrahim Abu-Salameh1, Ygal Plakht, Gal Ifergane

  • 1Headache Clinic, Department of Neurology, Soroka University Medical Center, Beer-Sheva, Israel.

The Journal of Headache and Pain
|July 24, 2010
PubMed
Summary
This summary is machine-generated.

Ramadan fasting significantly increases migraine frequency and duration in observant Muslim migraine sufferers. Physicians should counsel patients on managing dehydration and caffeine withdrawal, and consider prophylactic treatment.

Related Experiment Videos

Last Updated: Jun 10, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Area of Science:

  • Neurology
  • Public Health

Background:

  • Fasting during Ramadan is a mandatory religious practice for Muslims.
  • Migraine is a common neurological disorder affecting millions worldwide.
  • The impact of Ramadan fasting on migraine frequency requires further investigation.

Purpose of the Study:

  • To evaluate the effect of Ramadan fasting on migraine attack frequency in observant Muslim migraine sufferers.
  • To identify factors influencing migraine exacerbation during Ramadan.

Main Methods:

  • A cohort cross-over study design was employed.
  • Thirty-two observant Muslim migraine sufferers recorded migraine details in a diary.
  • Data was collected during the Ramadan month and a subsequent control month.

Main Results:

  • Migraine sufferers experienced an average of 9.4 migraine days during Ramadan versus 3.7 days during the control month (p < 0.001).
  • Fasting was associated with longer migraine duration, lower attack frequency, and increased migraine with aura.
  • The exacerbation was less pronounced in patients with throbbing headaches and married individuals.

Conclusions:

  • Ramadan fasting is associated with a significant increase in migraine frequency and duration.
  • Healthcare providers should discuss potential Ramadan-related migraine exacerbation with Muslim patients.
  • Recommendations include counseling on hydration, caffeine withdrawal, and considering prophylactic pharmacological treatment.