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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...

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Related Experiment Video

Updated: Jun 10, 2026

Glycopeptide Capture for Cell Surface Proteomics
10:11

Glycopeptide Capture for Cell Surface Proteomics

Published on: May 9, 2014

Red blood cell proteomics.

E M Pasini1, M Mann, A W Thomas

  • 1Biomedical Primate Research Centre, Lange Kleiweg 139, 2288 GJ Rijswijk, The Netherlands.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|July 27, 2010
PubMed
Summary
This summary is machine-generated.

Proteomics offers a comprehensive view of red blood cell (RBC) proteins, advancing understanding in health and disease. Further studies integrating lipidomics and glycomics are needed for complete erythrocyte insights.

More Related Videos

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Related Experiment Videos

Last Updated: Jun 10, 2026

Glycopeptide Capture for Cell Surface Proteomics
10:11

Glycopeptide Capture for Cell Surface Proteomics

Published on: May 9, 2014

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Area of Science:

  • Hematology
  • Biochemistry
  • Proteomics

Background:

  • Red blood cells (erythrocytes) are vital for gas exchange.
  • Their unique characteristics and abundant supply have driven extensive research.
  • Proteomics is a recently applied technique to erythrocyte studies.

Purpose of the Study:

  • To review the methodology and limitations of proteomics in erythrocyte research.
  • To highlight the contributions of proteomics to understanding red blood cells.
  • To discuss advances in red blood cell fields due to comparative proteomics.

Main Methods:

  • Standard and comparative proteomics are employed.
  • Proteomics provides a global snapshot of the erythrocyte proteome.
  • Literature review of red blood cell proteomics studies.

Main Results:

  • Proteomics has provided unique insights into transfusion medicine, anemia, and parasite biology.
  • A growing body of literature characterizes red blood cells in health and disease using proteomics.
  • Comparative proteomics has advanced various red blood cell-related fields.

Conclusions:

  • Proteomics is crucial for erythrocyte research, offering a global protein view.
  • A complete understanding requires integrating proteomics with lipidomics, glycomics, and interactomics.
  • Further research is needed to fully elucidate erythrocyte functions and roles in disease.