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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

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Published on: November 4, 2010

Asthma and school commuting time.

Rob McConnell1, Feifei Liu, Jun Wu

  • 1Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. rmcconne@usc.edu

Journal of Occupational and Environmental Medicine
|July 27, 2010
PubMed
Summary
This summary is machine-generated.

Severe wheeze in asthmatic children is linked to shorter school commute times, suggesting potential impacts from on-road air pollution exposure. Further research is recommended.

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Published on: November 4, 2010

Murine Model of Allergen Induced Asthma
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Published on: April 13, 2010

Area of Science:

  • Environmental Health
  • Pediatric Respiratory Health
  • Epidemiology

Background:

  • Childhood asthma is a significant public health concern.
  • On-road air pollution exposure is a suspected environmental trigger for respiratory symptoms.
  • School commuting time can serve as a proxy for exposure to traffic-related air pollutants.

Purpose of the Study:

  • To investigate the association between school commuting time and asthma-related outcomes in elementary school children.
  • To explore the relationship between exposure to on-road air pollution, estimated by commute time, and severe wheeze symptoms.

Main Methods:

  • Utilized data from 4741 elementary school children enrolled in the Children's Health Study.
  • Assessed asthma prevalence and severe wheeze through parental reports.
  • Used time spent on school commute routes as a proxy for on-road air pollution exposure.

Main Results:

  • Severe wheeze in children with asthma was associated with increased commuting time (OR 1.54).
  • This association was more pronounced in children with commute times of 5 minutes or longer (OR 1.97).
  • No significant association was found between commuting time and overall asthma prevalence.

Conclusions:

  • Shorter school commuting times were associated with a higher likelihood of severe wheeze among children already diagnosed with asthma.
  • Findings suggest that on-road pollutant exposure during commutes may exacerbate asthma symptoms.
  • Further research is warranted to elucidate the specific effects of on-road pollutant exposure on pediatric asthma exacerbations.