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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
Placenta and umbilical cord abnormalities seen with stillbirth
Halit Pinar1, Marshall Carpenter
1Division of Perinatal and Pediatric Pathology, Brown University, Providence, Rhode Island 02905, USA. hpinar@wihri.org
Clinical Obstetrics and Gynecology
|July 28, 2010
Summary
Placental lesions in stillbirth are common but often lack clear causal significance. This study clarifies macroscopic and microscopic placental findings to aid in diagnosing fetal death causes.
Area of Science:
- Perinatology
- Pathology
- Obstetrics
Background:
- Placental lesions are frequently observed in stillbirth cases.
- The pathogenetic significance of many placental changes in stillbirth remains uncertain.
- Existing literature often lacks adequate controls and standardized descriptions of placental lesions.
Purpose of the Study:
- To describe frequently listed placental characteristics in stillbirth case series.
- To elucidate the role of macroscopic placental, cord, and membrane findings in diagnosing fetal death.
- To organize histological findings related to the pathogenesis of fetal death conditions.
Main Methods:
- Review of placental characteristics commonly reported in stillbirth literature.
- Description of macroscopic examination protocols for placental, cord, and membrane findings.
- Organization of histological findings relevant to fetal death pathogenesis.
Main Results:
- Macroscopic placental, cord, and membrane findings can offer diagnostic insights at delivery.
- Standardized handling and examination of the placenta optimize histopathological assessment.
- Histological findings provide a framework for understanding the pathogenesis of fetal death.
Conclusions:
- Understanding placental findings is crucial for diagnosing stillbirth.
- Standardized examination protocols enhance diagnostic accuracy.
- Further research is needed to clarify the pathogenetic significance of placental lesions.
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