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Updated: Jun 10, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
[Intravenous treatment with iron in bloodless medicine]
1Ceská Spolecnost Bezkrevní Medicíny, Brno. csbmcz@tiscali.cz
Abstract:
Iron and iron plus a recombinant erythropoietin in bloodless medicine often offer a viable and safe alternative to the blood transfusion. But i.v. iron is often underutilised. This particularly applies to pre-operative anaemia which is present in 20% of patients admitted for surgery where iron deficiency is the major contributor. Treatment with i.v. iron, with or without recombinant erythropoietin, reduces the need for peri-operative transfusion.
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