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Published on: January 12, 2022
Polycythemia vera and increased hemophilic factor VIII causing acute zonal occult outer retinopathy: a case report
Padmamalini Mahendradas1, Rohit Shetty, Kavitha Avadhani
1Uveitis and Ocular Immunology Services, Narayana Nethralaya, Bangalore, India. padmamalini_m@yahoo.co.in
Objective:
To report a case of acute zonal occult outer retinopathy (AZOOR) caused by Polycythemia and increased levels of Factor VIIIC.
Design:
Case Report - Interventional.
Methods:
We present a 23 year old male with blurring of vision and loss of lower visual fields in both eyes. Ocular examination suggested the possibility of AZOOR that was confirmed with Fluorescein Angiogram, Visual fields and Electroretinogram. Laboratory work up revealed polycythemia with increased Factor VIIIC. He was treated for the same.
Results:
Ocular symptoms improved within 24 hours of treatment with venesection and asprin.
Conclusions:
Polycythemia vera and increased factor VIIIC levels, both venous thromboembolic risk factors are treatable causes of AZOOR.
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