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Native chronic total occlusion recanalization after lower limb bypass graft occlusion: a series of nine cases
Osami Kawarada1, Yoshiaki Yokoi
1Department of Cardiology, Kishiwada Tokushukai Hospital, Kishiwada city, Osaka, Japan. kawarada@stanford.edu
Insights
Endovascular recanalization of native chronic total occlusions (CTOs) offers a promising approach for limb salvage in patients with bypass graft occlusion. This technique demonstrated high technical success and significant clinical improvement, preserving limbs effectively.
Area of Science:
- Vascular Surgery
- Endovascular Interventions
- Peripheral Artery Disease
Background:
- No established consensus exists for managing threatened limbs due to bypass graft occlusion.
- Bypass graft occlusion presents a significant challenge in treating lower limb ischemia.
Purpose of the Study:
- To evaluate the clinical utility of endovascular recanalization for native chronic total occlusions (CTOs) in cases of lower limb bypass graft occlusion.
- To assess the effectiveness of this endovascular strategy in limb salvage and symptom improvement.
Main Methods:
- Nine patients with limb-threatening ischemia underwent endovascular native CTO recanalization.
- Techniques included conventional intraluminal and subintimal angioplasty with stenting.
- Procedures targeted various arteries including iliofemoral, iliac, superficial femoral, and popliteal.
Main Results:
- Technical success was achieved in 89% of cases with no major complications.
- Significant improvements were observed in ankle-brachial index and skin perfusion pressure.
- Marked clinical symptom improvement (Rutherford class) and successful limb salvage were achieved in all successful recanalizations.
Conclusions:
- Endovascular recanalization of native CTOs is a viable and effective strategy for patients with lower limb bypass graft occlusion.
- The procedure shows satisfactory outcomes, including limb salvage and symptom relief.
- This preliminary study supports the use of endovascular recanalization in this challenging patient group.
Objective:
The aim of the study was to report the clinical utility of native chronic total occlusion (CTO) recanalization as an endovascular strategy in lower limb bypass graft occlusion.
Background:
There is no consensus on the best approach for threatened limbs in patients with graft occlusion.
Methods:
The subjects were nine consecutive patients with limb-threatening ischemia after bypass graft occlusion. Native CTO recanalization was attempted endovascularly using conventional intraluminal and subintimal angioplasty techniques supported by stents.
Results:
The mean age of the bypass grafts was 6.7 +/- 7.3 (range: 1-24) months and the mean number of previous lower limb bypass surgeries was 1.4 +/- 0.5 (range: 1-2). Native CTO recanalization was performed in the iliofemoral (n = 2), iliac (n = 2), superficial femoral (n = 3), popliteal (n = 1), and popliteal-tibial (n = 1) arteries. Technical success was achieved in 89% (8/9) of cases without complications or major adverse cardiovascular events. The ankle-brachial index and skin perfusion pressure of the foot significantly increased after revascularization, with marked improvement of clinical symptoms (Rutherford class: 4.5 +/- 1.1-->0.9 +/- 1.4, P < 0.001). Limb salvage was achieved in all successful recanalization cases during the mean follow-up time of 25 +/- 20 months (range: 9-60).
Conclusions:
In this preliminary study, endovascular recanalization of native CTO showed satisfactory outcomes in patients with bypass graft occlusion.
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