Torsade de pointes with short coupling interval.
Ben Van den Branden1, Eric Wever, Lucas Boersma
1Dept. of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands. b.van.den.branden@antoniusziekenhuis.nl
This study details a rare case of short-coupled Torsade de pointes (TdP) in a patient with a normal QTc interval. Autonomic nervous system imbalance may contribute to this unusual ventricular tachycardia.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Torsade de pointes (TdP) is a specific type of ventricular tachycardia (VT) typically linked to prolonged QT intervals (LQTS) and specific electrical coupling patterns.
- Conventional TdP is characterized by distinct QRS complex morphology, appearing to twist around the baseline with varying amplitude and polarity.
Observation:
- A unique case of TdP was observed in a patient presenting with a short-coupled interval.
- This patient exhibited a normal QTc interval and no evidence of underlying structural heart disease, diverging from typical TdP presentations.
Findings:
- The precise mechanisms driving this variant TdP remain elusive.
- A potential association with autonomic nervous system imbalance is hypothesized as a contributing factor.
Implications:
- Given the uncertain efficacy of anti-arrhythmic drugs, implantable cardioverter-defibrillators (ICDs) are considered a primary treatment.
- Catheter ablation targeting the premature ventricular beats initiating the arrhythmia may be a viable option for recurrent cases resistant to drug therapy.
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