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Infection and panniculitis
L Katie Morrison1, Ronald Rapini, C Beau Willison
1Department of Dermatology, University of Texas Health Sciences Center, Houston, Texas, USA. ktmoxie@gmail.com
Abstract:
Infection-induced panniculitis may result from a number of microbes including bacteria, fungi, and parasites. Viruses have also been implicated as a cause. This type of panniculitis can occur as a primary infection by direct inoculation of infectious microorganisms into the subcutaneous tissue, or secondarily via microbial hematogenous dissemination with subsequent infection of the subcutaneous tissue. Panniculitis is rarely viewed solely in terms of infectious causes. Also, subcutaneous infections are infrequently viewed in terms of infection-induced panniculitis but rather as cutaneous infections with subcutaneous involvement. Little information exists specifically on the subject of infection-induced panniculitis outside of the realm of case reports and case series. In this review, the present authors address panniculitis from the vantage point of infectious causes, focusing on those microorganisms with infection-induced panniculitis reports in the literature. Diagnosis and treatment are also discussed.
Insights
Infection-induced panniculitis, caused by bacteria, fungi, parasites, or viruses, can occur directly or spread through the bloodstream. This review focuses on infectious causes, diagnosis, and treatment of this rare condition.
Area of Science:
- Dermatology
- Infectious Diseases
- Pathology
Background:
- Panniculitis is inflammation of subcutaneous fat.
- Infection-induced panniculitis is a rare manifestation of microbial infections.
- Subcutaneous infections are often not categorized as panniculitis.
Purpose of the Study:
- To review infection-induced panniculitis from an infectious etiology perspective.
- To consolidate information on microorganisms causing infection-induced panniculitis.
- To discuss diagnostic and therapeutic approaches.
Main Methods:
- Literature review focusing on case reports and series.
- Analysis of infectious agents implicated in panniculitis.
- Synthesis of diagnostic and treatment strategies.
Main Results:
- Infection-induced panniculitis can stem from bacteria, fungi, parasites, and viruses.
- Infections can be primary (direct inoculation) or secondary (hematogenous spread).
- Limited data exists outside case reports.
Conclusions:
- Infection-induced panniculitis requires consideration of microbial causes.
- Further research is needed to better understand this condition.
- Comprehensive diagnostic and treatment guidelines are beneficial.
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