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Primary amyloidosis of the eyelid: a case report
Alessio Caggiati1, Antonnio Campanella, Stefania Tenna
1Plastic Surgery Department, Istituto Dermopatico dell'Immacolata, Rome, Italy.
In Vivo (Athens, Greece)
|July 30, 2010
Abstract:
The Authors describe a case of primary localized amyloidosis of the eyelids, focusing on diagnosis and possible treatment. The involment of several structures of the eyelid such as muscles, conjunctiva and puncta lacrimalia, as well as peculiar features of these proteinaceous deposits, suggest different combined procedures and precise timing in choosing the appropriated therapy.
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Amyloid Fibrils
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid Fibrils
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
