Related Experiment Video
Updated: Jun 10, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
[Sarcoidosis presenting as partial seizures. Report of one case]
Cristina Lidia Fernández-Rey1, Antonio Saiz Ayala, María Jesús Alvarez-Uría Tejero
1Sección de Neuroimagen, Servicio de Radiodiagnóstico, Hospital Universitario Central de Asturias, Oviedo, Spain. cristinarey80@hotmail.com
Abstract:
The nervous system is affected in 10% of patients with sarcoidosis. However, neurological disturbances are rarely the first manifestation of the disease. We report a 36-year-old woman presenting with partial seizures that generalized secondarily. Magnetic resonance showed a left parietal cortical-subcortical lesion with a minimal mass effect, moderate vasogenic edema and intense enhancement with intravenous contrast. A magnetic resonance spectroscopy disclosed a low aggressiveness profile, compatible with an inflammatory lesion. Angiotensin converting enzyme levels were normal. The lesion was excised and the pathological study showed the presence of granulomas with dubious necrosis. The patient was treated with antituberculous drugs. One year later, the lesion had grown and a thorax CT scan showed numerous mediastinal and hilar lymphadenopathies. A new determination of angiotensin converting enzyme disclosed elevated levels and the biopsy of mediastinal lymph nodes confirmed the presence of sarcoidosis.
Related Concept Videos
Seizures l: Introduction
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types
Epilepsy ll: Types
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Rocky Mountain Spotted Fever