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Updated: Jun 10, 2026

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Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
[Serial transverse enteroplasty for short bowel syndrome. Case report]
Felipe Bellolio R1, Julieta Klaassen L, Dahiana Pulgar B
1Departamentos de Cirugía Digestiva y División de Cirugía, Facultad de Medicina, Pontificia Universidad Católica de Chile, Valdivia, Chile. fbelloli@med.puc.cl
Summary
Serial transverse enteroplasty successfully lengthened a patient's small intestine, resolving short bowel syndrome. This surgical technique allowed for exclusive oral feeding post-operation, improving patient outcomes.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Abdominal Surgery
Background:
- Short bowel syndrome (SBS) significantly impairs nutrient absorption, often necessitating parenteral nutrition.
- Surgical interventions aim to increase intestinal length and absorptive capacity in SBS patients.
- Serial transverse enteroplasty (STEP) is a technique that lengthens the bowel while preserving its blood supply.
Observation:
- A 51-year-old female patient with SBS experienced recurrent complications requiring hospitalization.
- The patient underwent serial transverse enteroplasty, increasing her small intestinal length from 140 cm to 180 cm.
- Postoperatively, the patient developed intra-abdominal fluid collections and a septic episode with bacterial endocarditis.
Findings:
- Despite postoperative complications, the patient successfully transitioned to exclusive oral feeding within one month.
- Nutritional and fluid balance was achieved solely through oral intake.
- The patient maintained exclusive oral feeding with five daily bowel movements during ambulatory follow-up.
Implications:
- Serial transverse enteroplasty can be an effective option for SBS patients, potentially enabling oral feeding independence.
- Careful postoperative monitoring is crucial to manage potential complications like infections and fluid collections.
- This case highlights the potential for significant functional improvement in SBS patients following intestinal lengthening procedures.

