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Cat-scratch disease: ocular manifestations and visual outcome
André L L Curi1, Danuza Machado, Gustavo Heringer
1Department of Ophthalmology, Instituto de Pesquisa Clinica Evandro Chagas, IPEC-FIOCRUZ, R. Francisco Dutra 150/801, Cep: 24220-150, Icaraí, Niterói, Rio de Janeiro, Brazil. andre.curi@ipec.fiocruz.br
International Ophthalmology
|July 30, 2010
Summary
Cat-scratch disease (CSD) can cause serious eye problems, including retinal infiltrates and angiomatous lesions. Early diagnosis and antibiotic treatment are crucial for managing CSD ocular manifestations and preserving vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Medical Research
Background:
- Cat-scratch disease (CSD) is a bacterial infection transmitted by cats, often presenting with ocular complications.
- Uveitis reference centers are key in diagnosing and managing complex eye conditions like CSD.
Purpose of the Study:
- To detail the intra-ocular manifestations of cat-scratch disease (CSD).
- To analyze CSD cases diagnosed at two Brazilian uveitis reference centers between 2001 and 2008.
Main Methods:
- Retrospective case series study.
- Review of clinical records for patients diagnosed with CSD.
- Analysis of demographic, clinical, and ophthalmological data.
Main Results:
- Twenty-four CSD patients (mean age 27.04 years) were identified, with 66.6% reporting cat scratches and all reporting cat exposure.
- Common ocular findings included retinal infiltrates (29.7%) and angiomatous lesions (24.3%); neuroretinitis occurred in 16.2%.
- Bilateral disease was observed in 13 patients, and 66.6% experienced systemic symptoms; all had positive serum antibodies to Bartonella henselae.
Conclusions:
- Retinal infiltrates and angiomatous lesions are the most frequent intra-ocular findings in CSD.
- CSD can lead to significant visual impairment, highlighting the need for prompt diagnosis and management.
- Systemic antibiotic treatment may benefit patients with CSD ocular manifestations.
