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A graphene oxide-organic dye ionic complex with DNA-sensing and optical-limiting properties

Janardhan Balapanuru1, Jia-Xiang Yang, Si Xiao

  • 1Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

Angewandte Chemie (International Ed. in English)
|July 30, 2010
PubMed
Summary

No abstract available in PubMed .

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...