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Deforming arthropathy complicating primary biliary cirrhosis
The Journal of Rheumatology
|April 1, 1991
Summary
Systemic lupus erythematosus (SLE) and primary biliary cirrhosis (PBC) rarely occur together. This case highlights a unique patient with both conditions who developed severe, rheumatoid factor-negative destructive arthritis, prompting a review of liver disease and arthritis associations.
Area of Science:
- Rheumatology
- Hepatology
- Immunology
Background:
- Systemic lupus erythematosus (SLE) and primary biliary cirrhosis (PBC) are autoimmune diseases.
- Concurrent SLE and PBC are considered rare.
- Arthropathy is a known manifestation of SLE, but deforming and destructive arthritis without rheumatoid factor is unusual.