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A new rhodamine-based chemosensor for Cu2+ and the study of its behaviour in living cells
Liang Huang1, Xiao Wang, Guoqiang Xie
1State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, P. R. China.
Dalton Transactions (Cambridge, England : 2003)
|July 31, 2010
Abstract:
A new rhodamine-based chemosensor (L1) was synthesized, and it exhibits high sensitivity and selectivity for the copper cation over other commonly coexistent metal ions in aqueous solution. Upon the addition of Cu(2+), the spirolactam ring of L1 was opened and a 1 : 1 metal-ligand complex was formed. Fluorescent imaging of Cu(2+) in living cells is also successfully demonstrated.

