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Updated: Jun 10, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
[Allergic contact dermatitis for temporary "black henna" tattoos]
Ana I Sánchez Moya1, María E Gatica, Domingo García Almagro
1Servicio de Dermatología, Complejo Hospitalario ToledoBuenos Aires, España. anai.sanchezmoya@yahoo.es
Abstract:
Temporary 'black henna' tattoos, an increasingly popular body decoration in pediatric population, are associated with a growing incidence of adverse events. Black henna does not exist naturally, it is obtained from original henna after the addition of other compounds, among them paraphenilendiamine (PPD), which serves to darken the tattoo and allows greater precision to the design. PPD is known to be a strong sensitizer and increases the risk of allergic contact dermatitis. They may present as long lasting local reactions, and pigmentary sequels apart from problems with the future use of many products present in the daily life, as a result of sensitization by PPD. We report the case of an eleven-year old girl with an allergic contact dermatitis to black henna tattoo with a positive patch test to PPD, in order to warn against these types of temporary tattoos.
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