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Related Concept Videos

Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

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Updated: Jun 10, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
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Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Complications in spine surgery.

Rani Nasser1, Sanjay Yadla, Mitchell G Maltenfort

  • 1Temple University School of Medicine, Philadelphia, Pennsylvania, USA.

Journal of Neurosurgery. Spine
|August 3, 2010
PubMed
Summary
This summary is machine-generated.

Spine surgery complications are more frequent in thoracolumbar procedures and prospective studies. Retrospective reviews underestimate the true incidence of adverse events in spinal surgery.

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Last Updated: Jun 10, 2026

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Published on: November 8, 2024

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Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

Published on: February 14, 2025

Area of Science:

  • Orthopedics
  • Neurosurgery
  • Evidence-based medicine

Background:

  • The overall incidence of complications in spinal surgery remains unclear.
  • Previous studies have not critically assessed complication rates across different spinal regions or study designs.
  • Existing research often focuses on provider-centric metrics rather than patient perspectives.

Purpose of the Study:

  • To systematically review and critically assess complication rates in spinal surgery literature.
  • To compare complication incidences between cervical and thoracolumbar procedures.
  • To evaluate the impact of study design (prospective vs. retrospective) on reported complication rates.

Main Methods:

  • A systematic evidence-based review of MEDLINE-indexed articles using keywords 'spine surgery' and 'complications'.
  • Inclusion of 105 relevant studies (84 retrospective, 21 prospective) covering 79,471 patients.
  • Comparative analysis of complication rates based on spinal region (cervical/thoracolumbar) and study design.

Main Results:

  • An overall complication incidence of 16.4% was reported across 105 studies.
  • Complications were significantly higher in thoracolumbar (17.8%) versus cervical (8.9%) procedures.
  • Prospective studies reported higher complication rates (19.9%) than retrospective studies (16.1%), particularly for thoracolumbar surgery.

Conclusions:

  • Retrospective spine surgery studies significantly underestimate the actual incidence of complications.
  • Study design critically influences the reported complication rates in spinal surgery literature.
  • This analysis provides a comprehensive assessment of complication incidences across different spinal regions and study methodologies.