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Updated: Jun 10, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Post-embolisation flow disturbances at the basilar tip triggering the development of an arterial aneurysm. A case
G Rodesch1, P Van Bogaert, H Szliwowski
1Clinique de Neuroradiologie, Hôpital Erasme; Bruxelles, Belgium.
Insights
This case study details a child
Area of Science:
- Neurology
- Vascular Surgery
- Interventional Radiology
Background:
- Intracerebral and intraventricular hemorrhage in children can result from arteriovenous malformations (AVMs).
- Ruptured AVMs present with severe neurological deficits, including headaches, cranial nerve palsies, visual field defects, and aphasia.
Purpose of the Study:
- To describe the endovascular management of a pediatric patient with a large temporal lobe AVM.
- To highlight potential complications of AVM embolization and long-term sequelae, such as aneurysm formation.
Main Methods:
- Endovascular embolization using acrylic glue (Histoacryl) in two sessions to obliterate the AVM nidus.
- Management of an intra-procedural complication involving glue embolus in the basilar artery with anticoagulation.
- Long-term clinical and angiographic follow-up to monitor AVM treatment and detect delayed complications.
Main Results:
- Successful obliteration of approximately 90% of the AVM nidus.
- Temporary basilar artery complication managed successfully with anticoagulation, with no permanent neurological deficit.
- Development of a basilar tip aneurysm three years post-embolization, attributed to flow dynamics and vascular wall changes.
Conclusions:
- Endovascular embolization is an effective treatment for pediatric intracranial AVMs, though complications can occur.
- Long-term surveillance is crucial to identify delayed vascular changes, including aneurysm formation, secondary to altered hemodynamics.
- Management of basilar artery complications requires careful consideration of anticoagulation and potential thrombotic risk.
Summary:
We present the case of an ll-year-old boy with a large intracerebral and intraventricular haemorrhage due to rupture of a left temporal arteriovenous malformation. The child initially presented with severe headaches and meningism, right VIth nerve palsy, right hemianopsia, and expressive aphasia. After stabilization of his neurological status, the patient was embolised in two sessions with acrylic glue (Histoacryl(*)), obliterating nearly 90% of the nidus, the residual to be considered for gamma-knife radiosurgery. The first session of embolisation had been complicated, during retrieval of the microcatheter, by an erratic embolus of glue in the basilar artery. The child was kept for 24 hours under heparin anticoagulation in order to avoid any thrombosis, followed by aspirin. His neurological examination remained stable without worsening of his clinical condition. Further angiographic controls demonstrated the patency of the basilar artery itself with remodelling changes at the basilar tip, with preservation of the perforators in this region. Secondary dilatation of the basilar tip with development of an arterial aneurysm was noted three years after the accident, pointing to the importance of flow turbulence and vascular wall weakness in the development of an arterial aneurysm. The clinical follow-up of this patient is 3.5 years; his neurological status is stable with hemianopsia, mild dysphasia and memory difficulties. Further follow-up will be needed in order to determine the therapeutic requirement for the arterial aneurysm.
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