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Efficient Method for Imaging Murine Lungs that Preserves Spatial Dynamics of Fungal Spores in the Airways
Published on: December 13, 2024
Common and emerging fungal pulmonary infections
Li Yang Hsu1, Esther Shu-Ting Ng, Liang Piu Koh
1Department of Medicine, National University Health System, Singapore 119074, Singapore. liyang_hsu@yahoo.com
Infectious Disease Clinics of North America
|August 3, 2010
Summary
Fungal pulmonary infections are rising in immunocompromised individuals. Advances in diagnostics and therapeutics are improving outcomes for vulnerable patients, including transplant recipients.
Area of Science:
- Infectious Diseases
- Mycology
- Pulmonology
Background:
- Fungal pulmonary infections are increasingly prevalent due to a rise in immunocompromised patients.
- Previously low-pathogenicity fungi like molds are now causing invasive disease in severely immunocompromised hosts.
- Progress in managing these infections has lagged behind other infectious diseases.
Purpose of the Study:
- To provide an overview of endemic and emerging fungal pulmonary infections.
- To discuss recent advancements in the diagnosis and clinical management of these infections.
Main Methods:
- Literature review of endemic mycoses and emerging fungal pulmonary infections.
- Analysis of recent developments in diagnostic tools and therapeutic strategies.
- Focus on clinical management, particularly in vulnerable populations.
Main Results:
- Fungal infections are a growing concern, especially in immunocompromised individuals.
- Emerging fungal pathogens, including molds, are increasingly implicated in invasive diseases.
- Recent diagnostic and therapeutic advances show promise for improved patient outcomes.
Conclusions:
- Despite slow overall progress, new diagnostic and therapeutic approaches are enhancing the management of fungal pulmonary infections.
- Improved clinical outcomes are particularly noted in high-risk groups like solid organ and hematopoietic stem cell transplant recipients.
- Continued research and development are crucial for addressing the challenges posed by these infections.
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