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Updated: Jun 10, 2026

06:44
Isolation of Brain-infiltrating Leukocytes
Published on: June 13, 2011
[Reversible posterior leukoencephalopathy or brain tumor--case report]
Branka Ribarić1, Davorka Milat, Zeljka Petelin Gadze
1Klinika za neurologiju Medicinskog fakulteta Sveucilista u Zagrebu, Klinicki bolnicki centar Zagreb.
Lijecnicki Vjesnik
|August 4, 2010
Summary
Reversible posterior leukoencephalopathy (RPLE) syndrome, often linked to hypertension, causes neurological symptoms and brain edema. This case highlights its reversibility with prompt diagnosis and management.
Area of Science:
- Neurology
- Radiology
Background:
- Reversible posterior leukoencephalopathy (RPLE) syndrome presents with neurological deficits and characteristic MRI findings.
- Historically associated with hypertension, renal disease, or immunosuppression, RPLE is now recognized in diverse conditions.
Observation:
- A 72-year-old hypertensive woman presented with acute headache, confusion, visual disturbances, and hemiparesis.
- Brain MRI showed extensive white matter lesions in the parietooccipital regions, initially mimicking an expansive process.
Findings:
- Extensive diagnostic work-up confirmed the diagnosis of reversible posterior leukoencephalopathy syndrome.
- The patient's symptoms resolved, and follow-up MRI demonstrated complete resolution of the white matter lesions.
Implications:
- This case underscores the importance of considering RPLE in patients with acute neurological symptoms and hypertension.
- Early diagnosis and management of RPLE can lead to complete neurological recovery and lesion resolution.
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