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Related Experiment Video

Updated: Jun 10, 2026

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
06:52

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes

Published on: November 1, 2019

Advances in aptamers.

Muhammad Ali Syed1, Saima Pervaiz

  • 1Department of Biosciences, Comsats Institute of Information Technology, Islamabad, Pakistan. mirwah2000@yahoo.de

Oligonucleotides
|August 4, 2010
PubMed
Summary
This summary is machine-generated.

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Aptamers, or nucleic acid-based binders, are increasingly researched for diverse applications. Chemical modifications enhance aptamer stability and bioavailability, driving advancements in therapeutics and diagnostics.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Biotechnology

Background:

  • Aptamers are nucleic acid molecules selected via in vitro methods for specific binding.
  • They present advantages over antibodies, including chemical modification potential.
  • Research on aptamers has surged significantly since the 2000s.

Purpose of the Study:

  • To provide an overview of aptamer advancements.
  • To focus on research published since 2005.
  • To highlight the growing importance of aptamers in various scientific fields.

Main Methods:

  • Literature review focusing on aptamer research.
  • Analysis of publications since 2005.
  • Synthesis of information on aptamer applications and modifications.

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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

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Related Experiment Videos

Last Updated: Jun 10, 2026

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
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Kinetic Screening of Nuclease Activity using Nucleic Acid Probes

Published on: November 1, 2019

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
12:23

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

Main Results:

  • Aptamers demonstrate broad utility in therapeutics, diagnostics, and biosensing.
  • Chemical derivatization improves aptamer in vivo stability and bioavailability.
  • Significant growth in aptamer-related publications indicates expanding research interest.

Conclusions:

  • Aptamers are versatile molecules with increasing applications.
  • Advancements in chemical modification are key to their therapeutic potential.
  • Continued research is expanding the scope and impact of aptamer technology.