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Updated: Jun 10, 2026

Electrochemical Preparation of Poly(3,4-Ethylenedioxythiophene) Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
Published on: July 28, 2021
Screen-printed poly(3,4-ethylenedioxythiophene) (PEDOT): A new electrochemical mediator for
Georges Istamboulie1, Tomasz Sikora, Elena Jubete
1Université de Perpignan, Via Domitia, IMAGES, Bat. S, 52 Av. Paul Alduy, 66860 Perpignan Cedex, France.
Abstract:
This work describes the use of a PEDOT:PSS-based conductive polymer for designing AChE-based biosensors. The transducers were obtained directly by screen-printing a PEDOT:PSS suspension on the surface of thick film carbon electrodes. The obtained working electrodes showed a high conductivity when compared with electrodes modified with conventional mediators like cobalt phthalocyanine or tetracyanoquinodimethane. The PEDOT:PSS polymer was shown to be suitable for thiocholine oxidation, allowing the measurement of AChE activity at 100 mV vs Ag/AgCl. The high conductivity of PEDOT:PSS allowed the accurate detection of the organophosphate insecticide chlorpyrifos-oxon at concentrations as low as 4x10(-9)M, corresponding to an inhibition ratio of 5%.

