Related Experiment Video
Updated: Jun 10, 2026
10:46
Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
Stromal support for Descemet's membrane endothelial keratoplasty
Massimo Busin1, Amit K Patel, Vincenzo Scorcia
1Villa Serena Hospital, Department of Ophthalmology, Forlì, Italy. mbusin@yahoo.com
Ophthalmology
|August 4, 2010
Summary
Peripheral stromal support enhances Descemet
Area of Science:
- Ophthalmology
- Corneal Surgery
- Endothelial Keratoplasty
Background:
- Descemet's membrane endothelial keratoplasty (DMEK) is a surgical procedure for endothelial dysfunction.
- Graft preparation and attachment can be challenging in DMEK.
Purpose of the Study:
- To evaluate the efficacy of peripheral stromal support in DMEK surgery.
- To assess if this technique improves surgical outcomes and graft attachment.
Main Methods:
- A prospective case series involving 10 patients with Fuchs' endothelial dystrophy.
- Donor tissue was eccentrically punched to include a peripheral stromal support.
- Pneumatic dissection was used for graft preparation.
Main Results:
- All surgeries were completed in under 1 hour.
- A 100% graft attachment rate was achieved.
- Best spectacle-corrected visual acuity (BSCVA) of ≥ 20/40 was observed in all patients postoperatively, with an average endothelial cell loss of 24.1%.
Conclusions:
- Peripheral stromal support simplifies DMEK surgery.
- This technique appears to reduce complications and maintain favorable visual outcomes.
- It is a promising adjunct for improving DMEK procedures.
