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Long-term inactivation particle for voltage-gated sodium channels

Katarzyna Dover1, Sergio Solinas, Egidio D'Angelo

  • 1Department of Physiology,University of Pavia and Brain Connectivity Center, IRCCS C. Mondino, Via Mondino 2, I-27100 Pavia, Italy.

The Journal of Physiology
|August 4, 2010
PubMed
Summary

A novel accessory protein particle controls long-term sodium channel inactivation, impacting neuron firing. This discovery reveals a new mechanism for regulating neuronal excitability and action potential generation.

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