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Related Concept Videos

Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

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Related Experiment Video

Updated: Jun 10, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Mitral annuloplasty using a cardiac resynchronization device.

Andrabi Syed Manzoor Ali1, Khurshid Iqbal, Nisar Ahmed Trambu

  • 1Department of Cardiology, SKIMS, Soura, Srinagar 190010, India.

Indian Pacing and Electrophysiology Journal
|August 4, 2010
PubMed
Summary

A new device aims to simplify percutaneous transvenous mitral annuloplasty for mitral regurgitation. This innovation could help patients with low ejection fraction and cardiac resynchronization therapy needs.

Keywords:
Cardiac Resynchronization DeviceMitral annuloplasty

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Area of Science:

  • Cardiovascular medicine
  • Medical device innovation
  • Interventional cardiology

Background:

  • Mitral regurgitation is a significant complication in patients with heart failure.
  • Current percutaneous transvenous mitral annuloplasty techniques are complex and not suitable for all patients, particularly those with left ventricular leads.

Purpose of the Study:

  • To propose a novel device for percutaneous transvenous mitral annuloplasty.
  • To address the limitations of existing annuloplasty methods in patients requiring cardiac resynchronization therapy.
  • To simplify the mitral annuloplasty procedure.

Main Methods:

  • Development of a novel device integrating annuloplasty and cardiac resynchronization therapy capabilities.
  • Focus on a less invasive, transvenous approach for mitral valve repair.

Main Results:

  • The proposed device aims to overcome the limitations of current annuloplasty interventions.
  • It offers a potential solution for patients with functional mitral regurgitation and left ventricular leads.
  • The integrated approach is expected to simplify the overall intervention.

Conclusions:

  • The novel device presents a promising advancement in treating mitral regurgitation.
  • It has the potential to expand treatment options for heart failure patients.
  • Further development and clinical trials are warranted to validate its efficacy and safety.