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[Studies on the chemical constituents of Ligularia macrophylla]
Qian-Qian Tian1, Guo-Yin Wang, Zhi-Ping Wen
1College of Pharmacy, Shihezi University, Shihezi 832002, China.
Objective:
To study the chemical constituents of Ligularia macrophylla.
Methods:
Isolation and purification were carried out on repeated silica gel column chromatography. The structures of the compounds were identified by physico-chemical properties and spectral analyses.
Results:
Eight compounds were isolated and identified as kaempferol (1), 2,4'-dihydroxy-5-methoxychalcone (2), 5-hydroxy-3,4', 7-trimethoxyflavone (3), isobutyl ester terephthalic acid (4), 4-hydroxybenzaldehyde (5), mono (2-ethylhexyl) terephthalate (6), lupeol (7), beta-sitosterol (8).
Conclusion:
Compounds 1 - 7 are isolated from this plant for the first time.
