Related Experiment Video
Updated: Jun 10, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
[Formula screening and optimizing for the dispersible tablets of breviscapine by orthogonal experiment]
1Department of Pharmacy, Shandong University, Jinan 250012, China. dyanan1696@sina.com
Objective:
To establish a suitable formulation for the dispersible tablets of brevisicapine.
Methods:
To prepare and optimize the breviscapine dispersible tablets by orthogonal experiment design using disintegration time as the index. The quality of breviscapine dispersible tablets was evaluated by the initial stability test.
Results:
The disintegration time of optimized prescription formulation was 89 s. L-HPC and CMS-Na were used by combining exterior and interior and the dissolution percent in vitro was obviously superior to the conventional tablets, and the quality of the dispersible tablets was very good in stability test.
Conclusion:
The formulation screened out for the dispersible tablets of breviscapine is reasonable, stable and suitable for the production on a large scale.
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