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The EVAR Trial 1: has it led to a change in practice?
Insights
The publication of EVAR Trial 1 data did not immediately alter endovascular aneurysm repair (EVAR) rates. However, a long-term trend shows increased EVAR procedures, now surpassing open repairs (OR).
Area of Science:
- Vascular Surgery
- Clinical Practice Impact
- Health Services Research
Background:
- The EVAR Trial 1 results, published in June 2005, provided crucial data on endovascular aneurysm repair (EVAR) versus open repair (OR) for abdominal aortic aneurysms (AAAs).
- Assessing the immediate and long-term impact of landmark trial publications on clinical practice is essential for understanding healthcare evolution.
Purpose of the Study:
- To evaluate the effect of the EVAR Trial 1 publication on the adoption of EVAR in a specific clinical setting.
- To compare practice patterns before and after the EVAR Trial 1 publication, and over a longer period.
Main Methods:
- A retrospective analysis of all abdominal aortic aneurysm (AAA) repairs performed at a single center.
- Comparison of data from the year preceding and the year following the EVAR Trial 1 publication (July 2004 - June 2006).
- Extended comparison with data from the preceding six years (January 2000 - December 2006).
Main Results:
- The proportion of EVARs performed did not significantly change in the year immediately following the EVAR Trial 1 publication (52% vs. 57%, p=0.64).
- A significant decrease in the mean age of patients undergoing open repair (OR) was observed post-publication (69 vs. 72 years, p<0.05), without a change in their physiological fitness.
- An overall increase in EVAR utilization was noted from 28% in 2000 to 57% in 2006.
Conclusions:
- The EVAR Trial 1 publication did not cause an immediate shift in the percentage of EVARs performed at the center.
- Over a six-year period, there has been a consistent rise in EVAR procedures, leading to EVAR becoming the predominant method of AAA repair in this unit.
Objectives:
To assess whether the publication of the EVAR Trial 1 (June 2005) had an impact on practice in our centre.
Methods:
A retrospective study of all patients undergoing abdominal aortic aneurysm (AAA) repair in Leicester, from the year before publication of EVAR Trial 1 data to the year after (July 2004 - June 2006). Data from the study period was then compared with practice over the last six years (January 2000 - December 2006).
Results:
The proportion of endovascular aneurysm repairs (EVARs) did not change significantly in the year following publication of EVAR Trial 1 data (52% VS 57%, p=0.64). The mean age of patients offered open repair (OR) fell in the year following publication (69 years +/- 6.68 vs 72 years +/- 5.71, p<0.05). Despite this, there was no significant change in their fitness (physiological POSSUM scores: 19.2 +/- 3.91 vs 18.2 +/- 3.74, P=0.30). There was an overall increase in the percentage of EVARs in the years 2000 (28%) to 2006 (57%).
Conclusion:
There was no significant difference in the percentage of EVARs between the two years of study. However, over the last six years, there has been an increasing number performed in our unit and we now do more EVARs than ORs.
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