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Updated: Jun 10, 2026
06:28
Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia
Published on: May 27, 2022
[L-carnitine: safe and effective for asthenozoospermia]
Ya-xuan Wang1, Shu-wen Yang, Chang-bao Qu
1Department of Urology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, China. wangyaxuan2003@yahoo.com.cn
Zhonghua Nan Ke Xue = National Journal of Andrology
|August 6, 2010
Summary
L-carnitine supplementation significantly improved sperm motility and increased pregnancy rates in men with asthenozoospermia. This treatment option is safe and effective for male infertility.
Area of Science:
- Reproductive Medicine
- Andrology
- Male Infertility Research
Context:
- Asthenozoospermia is a primary cause of male infertility with limited treatment options.
- Sperm motility is a critical factor in male fertility.
- Evaluating novel therapeutic agents for asthenozoospermia is crucial.
Purpose:
- To investigate the clinical efficacy of L-carnitine in infertile males diagnosed with asthenozoospermia.
- To assess the impact of L-carnitine on sperm parameters and pregnancy rates.
- To determine the safety profile of L-carnitine treatment.
Summary:
- A randomized controlled trial involving 135 patients with asthenozoospermia compared L-carnitine plus vitamin E versus vitamin E alone for 3 months.
- L-carnitine treatment significantly increased the percentage of forward motile sperm (45.4% vs. 28.6%) and pregnancy rates (31.1% vs. 3.8%).
- No significant changes in sperm density or morphology were observed, and no adverse events were reported.
Impact:
- L-carnitine demonstrates significant potential as a safe and effective treatment for improving sperm motility.
- The findings suggest L-carnitine can enhance fertility outcomes in men with asthenozoospermia.
- This study provides evidence supporting L-carnitine as a valuable therapeutic option in reproductive medicine.
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