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Related Experiment Video

Updated: Jun 10, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Gastroschisis: an update.

Andrew J A Holland1, Karen Walker, Nadia Badawi

  • 1Douglas Cohen Department of Paediatric Surgery, The Children's Hospital at Westmead, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia. andrewh3@chw.edu.au

Pediatric Surgery International
|August 6, 2010
PubMed
Summary
This summary is machine-generated.

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Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...

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Gastroschisis (GS) incidence is rising, particularly in young mothers. While antenatal diagnosis is common, optimal delivery timing and surgical techniques for GS require further research, though survival rates are high.

Area of Science:

  • Pediatric Surgery
  • Maternal-Fetal Medicine
  • Neonatology

Background:

  • Gastroschisis (GS) incidence is increasing globally, with rates of 4-5 per 10,000 live births.
  • Young maternal age is a primary risk factor, showing the largest increase in GS cases.
  • The significance of other risk factors like smoking and drug use may be less pronounced than initially thought.

Purpose of the Study:

  • To review current understanding and management of gastroschisis.
  • To evaluate the diagnostic and therapeutic implications of antenatal ultrasound findings.
  • To assess outcomes and identify areas for improved care standards.

Main Methods:

  • Review of epidemiological data on gastroschisis incidence and risk factors.
  • Analysis of antenatal diagnosis rates and their impact on delivery management.

Related Experiment Videos

Last Updated: Jun 10, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

  • Evaluation of surgical techniques and outcomes in centers with pediatric surgical facilities.

    • Main Results:

    • Over 90% of gastroschisis cases are diagnosed prenatally via ultrasound.
    • No clear evidence supports routine early delivery or elective C-section for antenatal GS diagnosis.
    • Delivery at specialized pediatric surgical centers reduces infant morbidity.
    • Survival rates for gastroschisis now exceed 90%.

    Conclusions:

    • While survival rates for gastroschisis are high, optimal delivery timing and surgical approaches remain subjects of ongoing investigation.
    • Long-term developmental outcomes for infants with gastroschisis appear generally normal or near-normal, warranting further study.
    • Standardizing care at specialized centers is crucial for minimizing morbidity in gastroschisis cases.