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Related Experiment Video

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Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

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Voiding urosonography with second-generation contrast agent versus voiding cystourethrography.

Eva Kis¹, Anna Nyitrai, Ildikó Várkonyi

¹1st Department of Pediatrics, Pediatric Radiology Unit, Semmelweis Medical University, 53-54 Str. János Bókay, Budapest, Hungary. kiseva2009@gmail.com

Pediatric Nephrology (Berlin, Germany)

|August 6, 2010

Summary

This summary is machine-generated.

Contrast-enhanced voiding urosonography (VUS) is a more sensitive method for diagnosing vesicoureteric reflux (VUR) in children than traditional voiding cystourethrography (VCUG). VUS offers superior detection and grading of VUR.

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Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

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Published on: June 21, 2024

Area of Science:

Pediatric Urology
Diagnostic Imaging
Radiology

Background:

Vesicoureteric reflux (VUR) is a common condition in children.
Contrast-enhanced voiding urosonography (VUS) is an emerging diagnostic tool for VUR.
Fluoroscopic voiding cystourethrography (VCUG) is the current standard for VUR diagnosis.

Purpose of the Study:

To evaluate the diagnostic sensitivity of VUS using a second-generation ultrasound contrast agent.
To compare the efficacy of VUS with standard fluoroscopic VCUG in detecting and grading VUR.
To determine the optimal imaging modality for VUR diagnosis in pediatric patients.

Main Methods:

A prospective study involving 183 children with 366 kidney-ureter units (KUUs).
Simultaneous VUS and VCUG performed during the same session with identical catheterization.
VUS utilized intravesical administration of a second-generation ultrasound contrast agent (SonoVue).

Main Results:

VUR was detected in 38% of KUUs.
VUS identified 37 additional cases of VUR missed by VCUG (10.1% of total).
VUS demonstrated significantly higher detection rates (p<0.00001) and moderate agreement in VUR grading compared to VCUG.

Conclusions:

Contrast-enhanced harmonic VUS with a second-generation contrast agent is superior to VCUG for VUR detection and grading.
VUS should be considered the preferred imaging method for diagnosing VUR in children.
This advanced VUS technique enhances diagnostic accuracy and patient management for VUR.