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A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools
Published on: August 21, 2019
A brief introduction to RNAi and microRNAs in stem cells
1Department of Physiology, East Carolina University, School of Medicine, Greenville, NC, USA.
Methods in Molecular Biology (Clifton, N.J.)
|August 6, 2010
Abstract:
Recently, RNAi, including microRNAs (miRNAs), has become an important tool to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short chapter, we will give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We will also discuss RNAi as a tool to study stem cell function and the potential future practical applications.
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