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Updated: Jun 10, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
Resource utilization and outcomes of intoxicated drivers
Robert A Cherry1, Pamela A Nichols, Theresa M Snavely
1Penn State Milton S, Hershey Medical Center, Department of Surgery, Shock Trauma Center, Hershey, Pennsylvania 17033, USA. rcherry@psu.edu.
Intoxicated drivers in motor vehicle crashes showed a trend towards reduced mortality and shorter hospital stays compared to non-intoxicated drivers. Further research is needed to confirm these findings regarding alcohol impairment and patient outcomes.
Area of Science:
- Trauma research
- Alcohol-related injuries
- Clinical outcomes
Background:
- High-risk behaviors of intoxicated drivers, including impaired reaction time and lack of seatbelt use, raise concerns about injury severity and clinical outcomes.
- This study investigates whether pre-hospital alcohol consumption influences injury severity scores and patient outcomes in motor vehicle crash (MVC) drivers.
Purpose of the Study:
- To compare injury severity and clinical outcomes between intoxicated and non-intoxicated drivers involved in motor vehicle crashes.
- To describe resource utilization for treating intoxicated versus non-intoxicated drivers at a Level 1 trauma center.
Main Methods:
- Retrospective descriptive study analyzing data from January 2002 to June 2007.
- Compared drivers with blood alcohol levels (BAC) > 80 mg/dL (ETOH > 80) against those with BAC = 0 mg/dL (ETOH = 0).
- Excluded drivers with no BAC drawn or BAC levels between 1-80 mg/dL; collected data on demographics, injury severity, outcomes, and resource utilization.
Main Results:
- No significant difference in Injury Severity Score (ISS) or complications between groups.
- A trend towards decreased mortality was observed in the intoxicated group (p=0.06).
- Non-intoxicated drivers (ETOH=0) had longer ICU LOS, hospital LOS, and ventilator days (p<0.05); intoxicated drivers were more often self-pay and incurred lower hospital charges and costs.
Conclusions:
- Intoxicated drivers demonstrated a trend towards better outcomes, including reduced mortality and shorter hospital stays.
- Further multivariable analysis is recommended to ascertain if acute intoxication, intubation, or ICU admission, rather than injury severity, drives these observed outcome differences.
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