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Published on: August 9, 2024
Ocular sarcoidosis in Thailand
K Pathanapitoon1, J H M Goossens, T C van Tilborg
1Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. kpathana@mail.med.cmu.ac.th
Pulmonary sarcoidosis is uncommon in Thai uveitis patients, but posterior multifocal chorioretinitis may indicate its presence. Early diagnosis of sarcoidosis in uveitis patients is crucial for better outcomes.
Area of Science:
- Ophthalmology
- Pulmonology
- Radiology
Background:
- Uveitis is an inflammatory eye condition with diverse causes.
- Sarcoidosis is a systemic inflammatory disease that can affect the lungs and eyes.
- Early diagnosis of sarcoidosis is essential for effective management and preventing complications.
Purpose of the Study:
- To determine the prevalence of pulmonary sarcoidosis in patients diagnosed with uveitis at a Thai referral center.
- To describe the clinical characteristics of uveitis patients with co-existing pulmonary sarcoidosis.
Main Methods:
- Retrospective review of radiological examinations for 209 new uveitis patients.
- Analysis of chest X-rays (CXRs) and chest CT scans.
- Review of clinical data for patients with suspected pulmonary sarcoidosis.
Main Results:
- One out of 209 patients showed radiological signs of stage 1 pulmonary sarcoidosis on CXR.
- Chest CT identified pulmonary sarcoidosis in three patients with posterior multifocal chorioretinitis (PMC).
- PMC patients were females over 50, asymptomatic for pulmonary issues, with normal CXRs.
Conclusions:
- Ocular sarcoidosis appears prevalent in Thailand.
- Pulmonary sarcoidosis may be underdiagnosed in uveitis patients.
- Increased suspicion and ancillary testing could improve sarcoidosis identification in uveitis cases.
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