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Lung transplantation in autoimmune diseases
1Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Clinics in Chest Medicine
|August 10, 2010
Summary
Lung transplantation is now a viable option for advanced lung diseases. This review covers lung transplant considerations for patients with autoimmune diseases, who are currently underrepresented.
Area of Science:
- Cardiology and Pulmonology
- Immunology and Autoimmune Diseases
Background:
- Lung transplantation has advanced significantly over 45 years.
- It is an accepted therapy for select patients with advanced lung diseases.
- Patients with autoimmune diseases represent a small fraction of lung transplant recipients.
Purpose of the Study:
- To review issues relevant to lung transplant candidates and recipients.
- To specifically address considerations for patients with autoimmune diseases.
Main Methods:
- Literature review of lung transplantation in patients with autoimmune diseases.
- Analysis of factors contributing to the low transplant rate in this population.
Main Results:
- Autoimmune diseases are an underutilized indication for lung transplantation.
- Multifactorial reasons contribute to the low transplant numbers in these patients.
Conclusions:
- Further research and clinical attention are needed to optimize lung transplantation outcomes for patients with autoimmune diseases.
- Understanding specific challenges is crucial for expanding access and improving results.
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