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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: Jun 10, 2026

Intravitreal Injections in the Ovine Eye
03:37

Intravitreal Injections in the Ovine Eye

Published on: July 5, 2022

Intravitreal triamcinolone.

Yong Tao1, Jost B Jonas

  • 1Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht Karls University, Heidelberg, Germany.

Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
|August 10, 2010
PubMed
Summary
This summary is machine-generated.

Intravitreal triamcinolone acetonide remains valuable for various eye conditions despite newer drugs. It is effective for macular edema, vein occlusions, and uveitis, but carries risks like ocular hypertension and cataract.

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Intravitreal triamcinolone acetonide (IVTA) was once the leading intravitreal injection.
  • Newer anti-VEGF agents have shifted its primary role.

Purpose of the Study:

  • To provide an updated review on the clinical use of intravitreal triamcinolone acetonide.

Main Methods:

  • Literature review of studies on triamcinolone acetonide in ophthalmology.

Main Results:

  • IVTA is still used for diabetic macular edema, retinal vein occlusions, uveitis, and ocular hypotony.
  • Common complications include secondary ocular hypertension (approx. 40%), cataract, and endophthalmitis.
  • It is also used in combination with bevacizumab or ranibizumab.

Conclusions:

  • Intravitreal triamcinolone acetonide remains a viable treatment option for various intraocular disorders due to its potent anti-inflammatory effects.
  • Its broad therapeutic window and efficacy make it a promising agent for combination therapies.