Masked hypertension: evidence of the need to treat

Gbenga Ogedegbe1, Charles Agyemang, Joseph E Ravenell

  • 1Center for Healthful Behavior Change, Division of General Internal Medicine, New York University School of Medicine, 423 East 23rd Street #15-168N, New York, NY 10010, USA. Olugbenga.Ogedegbe@nyumc.org

Insights

Masked hypertension, diagnosed using accurate home monitoring, significantly increases cardiovascular risks. Early identification and treatment are crucial for reducing patient morbidity and mortality.

Area of Science:

  • Cardiology
  • Hypertension Management
  • Preventive Medicine

Background:

  • Masked hypertension poses significant cardiovascular risks, comparable to sustained hypertension.
  • Home blood pressure monitoring (HBPM) now offers accurate diagnosis, similar to ambulatory blood pressure monitoring (ABPM).
  • Target organ damage is well-documented in patients with masked hypertension.

Purpose of the Study:

  • To review the cardiovascular prognosis of masked hypertension versus sustained hypertension.
  • To examine the impact of masked hypertension on target organ damage.
  • To propose a treatment algorithm for masked hypertension and discuss implementation challenges.

Main Methods:

  • Review of clinic-based and population-based studies.
  • Analysis of evidence on cardiovascular morbidity and mortality.
  • Evaluation of the relationship between masked hypertension and target organ damage.

Main Results:

  • Masked hypertension is associated with increased cardiovascular morbidity and mortality.
  • Evidence supports blood pressure treatment to reduce cardiovascular events.
  • Active identification and treatment of masked hypertension are warranted.

Conclusions:

  • Masked hypertension requires active identification and management.
  • Treatment strategies for masked hypertension should align with those for sustained hypertension.
  • Careful consideration of potential pitfalls is necessary for effective implementation.

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