[Computer micromorphometry of allotransplanted human kidneys]

Quantitative changes of structural correlations of transplanted allogenic human kidneys were examined in the histological slides by means of computer micromorphometry. The measurements were performed in 663 transplants selected randomly which had been in the recipient's body from several hours till 14.5 years. As a result of the study, parameters of glomeruli, tubules, blood vessels and connective tissue in the overall mass of donor kidneys were established starting from the time before transplantation and 6 months, 1-1.5, 2-3, 4-5, 7-14.5 years after transplantation. A progressive increase of sclerotic changes in the transplant is confirmed and the hypotheses about their genesis are proposed.